Caltrate®: Wyeth Consumer Healthcare

Page 1 | 2

The same Caltrate^® that helps prevent bone loss may help keep your colon healthy, too.* According to a major clinical study, two Caltrate^® tablets a day helped some patients maintain a healthy colon by reducing the risk of recurrence of colon polyps, a risk factor for colon cancer.*

Although the association between calcium intake and the reduced risk of recurrence of colon polyps is preliminary and subject to ongoing research, the current state of research supports a link.

This study was published in the New England Journal of Medicine (Baron JA et al. 1999; 340: 101-107).^§

Caltrate^® was the brand of calcium supplement used in the study. Two tablets (1200 mg calcium) were taken daily.

The study lasted 4 years but positive effects were seen in as early as nine months.

Caltrate^® should supplement a healthy diet and regular excercise.

It is important to see your doctor for regular colon health screenings, even if you're taking calcium supplements. It is especially important if you have had colon polyps.

Page 1 | 2

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any
disease.
† Compared to original formula.
§Source: Baron, J.A., Beach, M., Mandel, J.S., van Stolk, R.U., Haile, R.W. , Sandler, R.S., Rothstein, R., Summers, R.W., Snover, D.C., Beck, G.J., Bond, J.H., Greenberg, E.R., Frankl, H., Pearson, L., Phil, M., Calcium Supplements for the Prevention of Colorectal Adenomas New England Journal of Medicine, 1999; 340(2). 101-107.