Wyeth Consumer Healthcare | Contact Us
 

The same Caltrate that helps prevent bone loss may help keep your colon healthy, too.* According to a major clinical study, two Caltrate tablets a day helped some patients maintain a healthy colon by reducing the risk of recurrence of colon polyps, a risk factor for colon cancer.*

Although the association between calcium intake and the reduced risk (19%) of recurrence of colon polyps is preliminary and subject to ongoing research, the current state of research supports a link.


This study was published in the New England Journal of Medicine (Baron JA et al. 1999; 340: 101-107).
Caltrate was the brand of calcium used in the study-two tablets daily (1200 mg calcium).
An effect was seen as early as 9 months and the study continued for 4 years.
Caltrate should supplement a healthy diet and regular exercise.
Even if you are taking calcium supplements, it is important to see your doctor on a regular basis for routine colon health screenings, especially if you have had colon polyps.

Positive Effects Of Calcium Supplements Seen In Less Than A Year

(NAPS†)-More good news about a simple strategy-taking a calcium supplement. A study shows that calcium supplements may have benefits that go beyond bones.

The clinical study, published in the New England Journal of Medicine, showed that men and women with a history of colorectal adenomas who took calcium supplements daily reduced their risk of recurrence of colorectal adenomas, or polyps. Polyps are small, tumor-like growths that can develop on the surfaces of the colon and rectum. They are known to be precursors of colorectal cancer.

Eight hundred and thirty-two patients were included in the study, which was part of the Calcium Polyp Prevention Study, funded by the National Institute of Health. Patients either received 1200 milligrams of elemental calcium (provided by Caltrate® brand calcium supplements) a day or placebos ("dummy pills"). Over the course of the four-year study, patients who took calcium supplements had a significant decrease in the risk of recurrence of an adenoma and a greater decrease in the overall number of adenomas.

"Adenomas may develop into colorectal cancer. Less than a year into the study we saw positive results due to calcium-fewer adenomas and so less potential for cancer," said John A. Baron, MD, MS, MSc, Professor of Medicine and of Community and Family Medicine, Dartmouth Medical School, and principal investigator of the study. An effect was seen at 9 months and the study continued for 4 years.

Colorectal cancer, or cancer of the colon and the rectum, is the third most common form of cancer in men and women, according to the American Cancer Society (ACS). In 2000, colorectal cancer was responsible for and estimated 56,300 deaths, accounting for about 11% of cancer deaths.

Back to Learning Center
© 2010 Wyeth Consumer Healthcare
This site is intended only for residents of the United States.